Pathogenetic Factors in the Development of Fibrous Dysplasia and McCune-Albright Syndrome. Current Review of the Literature
نویسندگان
چکیده
Many studies have been made in the past in an effort to understand the pathogenetic factors that are involved in the development of fibrous dysplasia and McCune-Albright syndrome. Recently, with the aid of cellular and molecular biology, the implication of G protein mutations have been demonstrated to be a crucial etiopathogenetic factor for the manifestations of these disorders. In this paper, we present the most recent data regarding the etiology of monostotic and polyostotic fibrous dysplasia, as well as of McCune-Albright Syndrome, and discuss different sights of the above disorders associated with molecular changes.
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